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Lymphoma

Lymphoma is a type of blood cancer that originates in the lymphatic system, an essential part of the immune system. It develops when lymphocytes (a type of white blood cell) grow and multiply uncontrollably, forming tumors in lymph nodes and other tissues. This disrupts the body’s ability to fight infections and may spread to other organs.

Lymphomas are broadly divided into two main categories: Hodgkin Lymphoma and Non-Hodgkin Lymphoma, each with distinct characteristics and treatment approaches.

Types of Lymphoma

1. Hodgkin Lymphoma (HL)

  • Marked by the presence of Reed–Sternberg cells
  • More common in young adults
  • Often starts in the upper body (neck, chest, armpits)
  • High cure rates with timely treatment

2. Non-Hodgkin Lymphoma (NHL)

  • Includes a wide variety of lymphoid cancers
  • Can occur at any age, more common in older adults
  • May involve lymph nodes, spleen, bone marrow, or other organs
  • Some forms are slow-growing, others very aggressive

Causes and Risk Factors

The exact cause of lymphoma is not always clear, but several factors can increase risk:

  • Weakened immune system (e.g., HIV/AIDS, post-transplant)
  • Family history of lymphoma
  • Exposure to certain infections (e.g., Epstein–Barr virus, Helicobacter pylori)
  • Age (HL common in young adults; NHL more common after 60)
  • Exposure to chemicals, pesticides, or radiation

Symptoms of Lymphoma

Common warning signs include:

  • Painless swelling of lymph nodes (neck, armpits, or groin)
  • Persistent fatigue
  • Fever and night sweats
  • Unexplained weight loss
  • Itchy skin or persistent rash
  • Loss of appetite

If these symptoms persist, medical consultation is essential for early detection and treatment.


Diagnosis and Tests

Lymphoma is usually diagnosed through:

  • Physical examination and medical history
  • Blood tests
  • Lymph node biopsy – the gold standard for diagnosis
  • Imaging tests (CT, PET, MRI) – to check spread
  • Bone marrow biopsy – to detect bone marrow involvement

Treatment Options

Treatment depends on the type, stage, and overall health of the patient. Common approaches include:

  • Chemotherapy
  • Radiation therapy
  • Targeted therapy (e.g., monoclonal antibodies like Rituximab)
  • Immunotherapy (CAR-T cell therapy, checkpoint inhibitors)
  • Stem cell (bone marrow) transplant in advanced/refractory cases

Many patients achieve long-term remission, especially with advances in targeted and immune-based therapies.


Living with Lymphoma

Managing lymphoma involves not just treatment but also lifestyle and emotional support:

  • Counseling and psychological support
  • Healthy nutrition and exercise guidance
  • Patient support groups
  • Financial and rehabilitation assistance

Get Involved

You can contribute to the fight against lymphoma by:

  • Supporting awareness campaigns
  • Becoming a blood or stem cell donor
  • Contributing to research and treatment funding
  • Volunteering for patient care initiatives

Need Support?

  • If you or someone you know is affected by lymphoma, we're here to help. Contact us at [85 85 85 88 28].
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